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Overview

Review national guidelines for cancer screening and prevention; this information is listed by gene mutation and by cancer type.

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Factors that affect pancreatic cancer risk

Every person is at risk for pancreatic cancer and the risk increases with age. A person in the general population has about a 1 percent  lifetime risk of developing pancreatic cancer. This means that 1 out of every 100 people will get pancreatic cancer in their lifetime. 

Genes linked to pancreatic cancer risk 

The most common gene mutations associated with inherited pancreatic cancer are:

 


Inherited mutations in the following genes are linked to a type of pancreatic cancer known as endocrine pancreatic cancer.

  • CDKN1B
  • TET
  • MEN1
  • VHL

 


Other factors linked to pancreatic cancer risk

Factors such as diet, weight, exercise, smoking, alcohol consumption, and type 2 diabetes can affect pancreatic cancer risk in the general population. More research is needed to understand how much these factors influence risk in people with inherited mutations.

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  • Ask your how many patients with your mutation they care for, and what screening guidelines they follow. If your is not part of an established high-risk cancer prevention program, you may also ask whether they have any connections to research registries or other research studies for patients like you.
  • The National Cancer Institute (NCI)-designated comprehensive cancer centers deliver cutting-edge cancer care to patients in communities across the United States. Most centers have specialized screening and prevention centers for high risk people. Find a center near you and learn about its specific research capabilities, programs, and initiatives.
  • Register for the FORCE Message Boards to get referrals from other members. Once you register, you can post on the Find a Specialist board to connect with other people who share your situation.
Last updated January 06, 2024